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2024年9月5日星期四

饱和脂肪简史:科学共识的形成与瓦解

 饱和脂肪简史:科学共识的形成与瓦解


1  标题:

【饱和脂肪简史:科学共识的形成与瓦解】
A Short History of Saturated Fat: The Making and Unmaking of a Scientific Consensus


博客内容(中文部分)

1. 饱和脂肪的早期认识

20世纪初期,饱和脂肪逐渐被认为是饮食中的一种主要脂肪来源,特别是在肉类和奶制品中。随着心血管疾病(CVD)发病率的上升,科学家开始寻找其潜在的原因。Ancel Keys 领导的一项著名研究——“七国研究”——提出饱和脂肪摄入与心脏病发病率之间的联系。由此,饱和脂肪逐渐成为健康专家的重点关注对象,并促使了公共健康政策的改变。

2. 科学共识的形成

20世纪50年代至80年代间,多个研究陆续证实了高饱和脂肪摄入与胆固醇升高、动脉硬化及心脏病之间的关联。这一期间的营养指南普遍建议减少饱和脂肪的摄入,转而推荐多不饱和脂肪(如植物油)和低脂肪饮食。这种饮食建议深刻影响了几十年来的饮食习惯与健康观念。

3. 共识的动摇与挑战

然而,从90年代开始,越来越多的研究开始质疑饱和脂肪与心脏病之间的简单因果关系。例如,一些研究发现,仅凭减少饱和脂肪并不能显著降低心脏病发病率。此外,新的研究强调了不同类型的脂肪和饮食背景的复杂性,并开始重视糖类、精制碳水化合物对健康的负面影响。

4. 最新研究进展

近年来,越来越多的证据表明,适量摄入天然饱和脂肪并不一定会对心脏健康造成威胁。研究显示,天然饱和脂肪,如椰子油、草饲牛肉中的脂肪等,可能对机体产生中性甚至有益的作用。反式脂肪、工业化处理过的脂肪则被证明是导致炎症和心脏疾病的更大元凶。

5. 自然医学的观点

在自然医学中,饱和脂肪的合理摄入通常被视为整体健康的一部分,尤其是在强调全食物饮食和避免加工食品的背景下。现代自然疗法建议人们选择来源良好的饱和脂肪,如有机、草饲的动物脂肪和未加工的植物油,以促进整体健康,而非简单地追求“低脂饮食”。

6. 临床一线医生的指导建议

对于临床医生,建议不再仅依赖过时的“低脂饮食”理论。应根据患者个体情况,综合考虑其脂肪摄入的种类与量,尤其是区别天然饱和脂肪和加工脂肪。同时,应更加关注精制糖和高碳水化合物饮食的危害,结合最新的研究为患者制定个性化的饮食计划。


2  English Section

1. Early Understanding of Saturated Fat

In the early 20th century, saturated fat was widely recognized as a primary dietary fat, especially found in meat and dairy products. As cardiovascular disease (CVD) rates soared, scientists began investigating potential causes. Ancel Keys' famous "Seven Countries Study" suggested a link between saturated fat intake and heart disease, prompting a shift in public health policies.

2. Formation of Scientific Consensus

Between the 1950s and 1980s, numerous studies confirmed the association between high saturated fat intake, elevated cholesterol levels, atherosclerosis, and heart disease. As a result, dietary guidelines during this period broadly recommended reducing saturated fat and promoting polyunsaturated fats (like vegetable oils) and low-fat diets. This shaped eating habits and health perspectives for decades.

3. Challenges to the Consensus

From the 1990s onward, many studies started questioning the straightforward causal relationship between saturated fat and heart disease. For instance, research found that merely reducing saturated fat did not significantly lower CVD risk. Moreover, newer studies emphasized the complexity of different fat types and highlighted the harmful effects of sugar and refined carbohydrates on health.

4. Recent Scientific Advances

More recent evidence suggests that moderate consumption of natural saturated fats may not pose a significant risk to heart health. Studies show that natural saturated fats, such as those found in coconut oil and grass-fed beef, may have neutral or even beneficial effects on the body. Meanwhile, trans fats and industrially processed fats have been proven to cause inflammation and heart disease.

5. Perspective of Natural Medicine

In natural medicine, reasonable consumption of saturated fat is often viewed as part of holistic health, especially when emphasizing whole food diets and avoiding processed products. Modern naturopathy encourages the use of high-quality sources of saturated fat, such as organic, grass-fed animal fats and unprocessed plant oils, to promote overall health rather than blindly adhering to "low-fat" trends.

6. Practical Guidance for Clinicians

Clinicians are advised to move beyond outdated "low-fat diet" theories and instead focus on the type and quantity of fats patients consume. Differentiating between natural saturated fats and processed fats is key. Greater attention should also be paid to the risks of refined sugar and high-carbohydrate diets, with personalized dietary plans tailored to patients' needs based on the latest research.


通过网络资源扩充的内容可以进一步强调饱和脂肪与心脏健康的复杂性,讨论更多高质量的研究,并为医生提供个性化饮食建议的实际案例,以便更好地应用于临床实践。

4o



3   Copilot

这篇文章《饱和脂肪简史:科学共识的形成与瓦解》探讨了从20世纪50年代末至今的饮食与心脏假说的历史1。文章揭示了许多以前未在科学文献中发表的内容,包括美国心脏协会在发起饮食假说方面的作用及其潜在利益冲突1

文章指出,饱和脂肪导致心脏病的观点是在1950年代基于微弱的关联证据提出的1。后续的临床试验未能建立因果关系,但这些数据在很大程度上被忽视了几十年1。最近的重新评估表明,饱和脂肪对心血管疾病、心血管死亡率或总死亡率没有影响1

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4   帖子原文

饱和脂肪简史:科学共识的形成与瓦解

A short history of saturated fat: the making and unmaking of a scientific consensus


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