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2024年7月20日星期六

探索胰岛素抵抗对血压的隐秘影响

 探索胰岛素抵抗对血压的隐秘影响





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探索胰岛素抵抗对血压的隐秘影响

克里斯·博彻 @chrisboettcher9

高血压,常被称为无声的杀手,其鲜为人知的主要原因是:胰岛素抵抗。下面我们来仔细看看胰岛素如何影响血压,以及你可以做些什么来应对:

让我们来认识一下约翰。约翰40多岁,有三个孩子,偶尔喜欢吃汉堡和啤酒。尽管他最近努力吃得更健康,并且减掉了五磅,但在他的年度体检中,医生建议他服用降血压药物。约翰感到困惑,因为他的体重稳定,而且他已经减少了盐的摄入。潜在的问题是什么呢?胰岛素抵抗。

胰岛素由胰腺产生,通过让糖进入细胞以供能量来调节血糖水平。然而,有时候细胞会对胰岛素产生抵抗,导致胰腺产生更多的胰岛素来补偿。这种过量的胰岛素,被称为高胰岛素血症,可能导致严重的健康问题,包括高血压。胰岛素水平升高会导致身体保留更多的钠,增加水分保留和血压。此外,胰岛素会导致血管收缩,使其变窄,进一步提高血压。

胰岛素抵抗的发展很慢,通常没有明显的症状,而且定期体检可能会漏掉它,因为胰岛素水平并没有直接测量。预防高血压需要解决胰岛素抵抗。以下是一些管理胰岛素水平的建议:

  1. 定期运动:体育活动有助于身体更有效地利用胰岛素。目标是大多数天至少进行30分钟的适度运动,如步行、骑自行车或游泳。

  2. 健康饮食:关注富含纤维、低精炼糖的全食物,以保持稳定的血糖水平并减少胰岛素的激增。包括蔬菜、水果、瘦蛋白和全谷物。

  3. 保持健康体重:过重,特别是腹部的过重,是胰岛素抵抗的一个关键指标。即使是适度的减重也可以改善胰岛素敏感性。

  4. 限制加工食品:加工食品通常含有高糖和不健康的脂肪,有助于胰岛素抵抗。尽可能选择新鲜的全食物,并在家中烹饪。

  5. 保持水分:喝足够的水有助于肾脏管理钠水平,这对整体健康和血压控制至关重要。每天至少喝八杯水。

  6. 管理压力:压力会触发皮质醇和肾上腺素的释放,使胰岛素更难发挥作用,导致胰岛素产生增加。高压力还可能导致不健康的饮食和睡眠不足,加剧胰岛素抵抗。

理解和管理胰岛素抵抗至关重要,因为它是糖尿病、心脏病、中风和癌症等慢性疾病的一个重要因素。这些疾病通常是由胰岛素抵抗引起的长期炎症的结果【374†source】【375†source】。掌握自己的健康从认识到胰岛素抵抗的作用开始,并采取生活方式来逆转它。

更多详细的见解和实践步骤,请查看克里斯·博彻关于胰岛素抵抗的全面系列这里【375†source】。


**Exploring the Hidden Impact of Insulin Resistance on Blood Pressure**


**Chris Boettcher**

[@chrisboettcher9](https://x.com/chrisboettcher9/status/1813177794622292284)


High blood pressure, often called a silent killer, has a lesser-known leading cause: insulin resistance. Here’s a closer look at how insulin affects blood pressure and what you can do about it:


Meet John. In his early 40s, John has three kids and occasionally enjoys burgers and beer. Despite his recent efforts to eat healthier and losing five pounds, his doctor advised him to take blood pressure medication during his annual check-up. John was confused because his weight was stable, and he had reduced his salt intake. The underlying issue? Insulin resistance.


Insulin, produced by the pancreas, regulates blood sugar levels by allowing sugar to enter cells for energy. However, sometimes cells become resistant to insulin, causing the pancreas to produce more to compensate. This excess insulin, known as hyperinsulinemia, can lead to serious health issues, including high blood pressure. Elevated insulin levels cause the body to retain more sodium, increasing water retention and blood pressure. Additionally, insulin causes blood vessels to constrict, narrowing them and further raising blood pressure.


Insulin resistance develops slowly, often without noticeable symptoms, and regular check-ups may miss it as insulin levels aren't directly measured. Preventing high blood pressure requires addressing insulin resistance. Here are some tips to manage insulin levels:


1. **Regular Exercise**: Physical activity helps the body use insulin more efficiently. Aim for at least 30 minutes of moderate exercise most days, such as walking, cycling, or swimming.

2. **Healthy Diet**: Focus on fiber-rich, low-refined-sugar whole foods to maintain stable blood sugar levels and reduce insulin spikes. Include vegetables, fruits, lean proteins, and whole grains.

3. **Maintain a Healthy Weight**: Excess weight, particularly around the abdomen, is a key indicator of insulin resistance. Even modest weight loss can improve insulin sensitivity.

4. **Limit Processed Foods**: Processed foods are often high in sugar and unhealthy fats, contributing to insulin resistance. Opt for fresh, whole foods and cook at home when possible.

5. **Stay Hydrated**: Drinking plenty of water helps kidneys manage sodium levels, essential for overall health and blood pressure control. Aim for at least eight glasses of water a day.

6. **Manage Stress**: Stress triggers the release of cortisol and adrenaline, making it harder for insulin to function and leading to higher insulin production. High stress can also lead to unhealthy eating and poor sleep, exacerbating insulin resistance.


Understanding and managing insulin resistance is crucial as it is a significant factor in chronic diseases like diabetes, heart disease, stroke, and cancer. These diseases often result from long-term inflammation caused by insulin resistance【374†source】【375†source】. Taking control of your health starts with recognizing the role of insulin resistance and adopting a lifestyle to reverse it.


For more detailed insights and practical steps, check out the comprehensive series on insulin resistance by Chris Boettcher [here](https://brother2brotheruniversity.substack.com/p/insulin-resistance-what-is-it)【375†source】.


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